GOT1 inhibitor-1 Catalog No.:M14030-2 RAC1 inhibition targets amyloid precursor

RAC1 inhibition targets amyloid precursor protein processing by gamma-secretase and decreases Abeta production in vitro and in vivo

has no effect on EGF-R TK but maintains a high cytotoxic profile

InChiKey: MLKXDPUZXIRXEP-MFOYZWKCSA-N

Smiles: CC(NC(=O)C(CS)NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)CNC(=O)C(C)NC(=O)C(CC(O)=O)NC(=O)C(CS)NC(=O)C(CCSC)NC(=O)C1CCCN1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)CNC(=O)C(N)CC1C=CC(O)=CC=1)C(C)C)C(=O)NC(C(C)C)C(O)=O

Duocarmycin TM is an exceptionally potent antitumor antibiotic

GOT1 inhibitor-1 Catalog No.:M14030-2 RAC1 inhibition targets amyloid precursorGOT1 inhibitor 1 (compound 2c), a tryptamine based derivative, acts as a novel, potent and non covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with an IC50 of 8. 2 uM. GOT1 inhibitor 1 can be used for the research of pancreatic ductal adenocarcinoma (PDAC). Product information CAS Number: 732973 87 4 Molecular Weight: 354. 83 Formula: C19H19ClN4O Chemical Name: N (4 chlorophenyl) 4 (1H indol 4 yl)piperazine 1 carboxamide Smiles: