AMG 458 significantly inhibits tumor growth in the NIH3T3/TPR-Met and U-87 MG xenograft models at 30 and 100 mg/kg q
leading to cancer-specific cell death
potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses
62 nM (DYRK1B)
InChiKey: GCDHMGROXQUFNR-HEVIKAOCSA-N
Molindone-d8 Catalog No.:M24840-C AMG 458 significantly inhibits tumorMolindone d8 is the deuterium labeled Molindone. Molindone hydrochloride (EN 1733A) is a therapeutic antipsychotic, used in the treatment of schizophrenia, works by blocking the effects of dopamine in the brain, leading to diminished psychoses. Product information CAS Number: 1189805 13 7 Molecular Weight: 284. 42 Formula: C16H24N2O2 Chemical Name: 3 ethyl 2 methyl 5 {[(2,2,3,3,5,5,6,6 H)morpholin 4 yl]methyl} 4,5,6,7 tetrahydro 1H indol 4 one Smiles: