(3R,4S)-Tofacitinib - CAS# 1092578-46-5 lexin Hydrochloride InChi: InChI=1S/C54H84N8O11S2/c1-12-34(6)47(40(72-10)29-43(64)61-26-19-22-39(61)48(73-11)35(7)49(66)57-38(51-56-24-27-74-51)28-36-20-15-13-16-21-36)60(9)53(69)45(32(2)3)58-50(67)46(33(4)5)59(8)42(63)23-17-14-18-25-62-44(65)30-41(52(62)68)75-31-37(55)54(70)71/h13

InChi: InChI=1S/C54H84N8O11S2/c1-12-34(6)47(40(72-10)29-43(64)61-26-19-22-39(61)48(73-11)35(7)49(66)57-38(51-56-24-27-74-51)28-36-20-15-13-16-21-36)60(9)53(69)45(32(2)3)58-50(67)46(33(4)5)59(8)42(63)23-17-14-18-25-62-44(65)30-41(52(62)68)75-31-37(55)54(70)71/h13

The effect is more apparent in the 0

irreversible proteasome inhibitor (over 80% inhibition at doses of 10 nM and above)

CAS Number: 357166-30-4

2013 Apr12 [updated 2014 Sep 18]

(3R,4S)-Tofacitinib - CAS# 1092578-46-5 lexin Hydrochloride InChi: InChI=1S/C54H84N8O11S2/c1-12-34(6)47(40(72-10)29-43(64)61-26-19-22-39(61)48(73-11)35(7)49(66)57-38(51-56-24-27-74-51)28-36-20-15-13-16-21-36)60(9)53(69)45(32(2)3)58-50(67)46(33(4)5)59(8)42(63)23-17-14-18-25-62-44(65)30-41(52(62)68)75-31-37(55)54(70)71/h13Tofacitinib, also known as tasocitinib, CP 690550, is a Janus kinase (JAK) inhibitor. Product information CAS Number: 1092578 46 5 Molecular Weight: 312. 37 Formula: C16H20N6O Chemical Name: 3 [(3R,4S) 4 methyl 3 [methyl({7H pyrrolo[2,3 d]pyrimidin 4 yl})amino]piperidin 1 yl] 3 oxopropanenitrile Smiles: CN([C@H]1CN(CC[C@@H]1C)C(=O)CC#N)C1N=CN=C2NC=CC2=1 InChiKey: UJLAWZDWDVHWOW AAEUAGOBSA N InChi: InChI=1S C16H20N6O c1 11 5 8 22(14(23)3 6 17)9