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CuATSM l-3-O-(2''-O-β-D-glucopyl)-β-D-rutinoside Medicarpin induces apoptosis and overcome

SKU: 34085707865

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Description

Medicarpin induces apoptosis and overcome multidrug resistance in leukemia P388 cells by modulating P-gp-mediated efflux of drugs

Muscarine iodide (1-30 μM) produces a dose-dependent hyperpolarization in a sub-population of the NRM cells that contain 5-hydroxytryptamine (5-HT) on the NRM neurons

3MB-PP1 was not able to significantly inhibit Pti1 and MPK2

Pyrazole ligands: structure-affinity/activity relationships and estrogen receptor-alpha-selective agonists

PF-CBP1 inhibits CREBBP and EP300 bromodomains with IC50 of 125 nM and 363 nM respectively

CuATSM l-3-O-(2''-O-β-D-glucopyl)-β-D-rutinoside Medicarpin induces apoptosis and overcomeCuATSM is a highly potent radical trapping antioxidant (RTA) and inhibitor of (phospho)lipid peroxidation, thereby accounting for its (their) ability to inhibit ferroptosis. The metallo protein Cu Zn superoxide dismutase (SOD1) is a ubiquitous enzyme responsible for scavenging superoxide radicals. Mutations in SOD1, which alter its metal binding capacity and can result in protein misfolding and aggregation, have been linked to familial amyotrophic

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