Destruxin B - CAS# 2503-26-6 nelate 9-trioxa-12-azatetradec-1-yl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamide

9-trioxa-12-azatetradec-1-yl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamide

Formula: C24H34N4O5S

induces apoptosis and inhibits migration

Chemical Name: propan-2-yl (2Z)-3-{3-[3-methoxy-5-(trifluoromethyl)phenyl]-1H-1

and Ret receptors

Destruxin B - CAS# 2503-26-6 nelate 9-trioxa-12-azatetradec-1-yl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamideDestruxin B, isolated from entomopathogenic fungus Metarhizium anisopliae, is one of the cyclodepsipeptides with insecticidal and anticancer activities. Destruxin B induces apoptosis via a Bcl 2 Family dependent mitochondrial pathway in human nonsmall cell lung cancer cells. Destruxin B significantly activates caspase 3 and reduces tumor cell proliferation through caspase mediated apoptosis, not only in vitro but also in vivo. Product information CAS