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More than a decade ago, Kightlinger started his PhD and postdoc in Jewett's lab at Northwestern, engineering enzymes to fix cell-free glycosylation

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While originally The Bully and disgusted at the other protagonists, Ryousuke is presented quite sympathetically due to his back story and poor home life

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[41] To emphasize Belle's independence, Woolverton rewrote the character to willingly search for her father at the castle, where she confronts the Beast and offers to take Maurice's place